STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PMG11_03444Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1210 aa)    
Predicted Functional Partners:
PMG11_06920
Telo_bind domain-containing protein.
    
 0.977
PMG11_09083
Uncharacterized protein.
   
 
 0.952
PMG11_02178
ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase.
   
 
 0.933
PMG11_08653
Putative ATP-dependent DNA helicase II subunit 1.
    
 
 0.929
PMG11_10917
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 
 0.916
PMG11_01057
Putative Centromere/microtubule-binding protein cbf5.
    
 0.903
PMG11_04710
Putative DNA repair protein Rad50.
    
 
 0.888
PMG11_06705
Uncharacterized protein.
    
 0.864
PMG11_07267
Putative Pseudouridine synthase.
    
 0.858
PMG11_04049
Putative Small nuclear ribonucleoprotein complex protein Nhp2.
    
 0.850
Your Current Organism:
Penicillium brasilianum
NCBI taxonomy Id: 104259
Other names: ATCC 12072, CBS 253.55, FRR 3466, P. brasilianum, Penicillium sp. 028M, Penicillium sp. FKI-3368, QM 6947
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.