STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PMG11_04953Telomere_reg-2 domain-containing protein. (1008 aa)    
Predicted Functional Partners:
PMG11_09657
Uncharacterized protein.
    
 0.993
PMG11_01503
Putative UVSB PI-3 kinase; Belongs to the PI3/PI4-kinase family.
    
 0.966
PMG11_02294
HRDC domain-containing protein.
    
 0.962
PMG11_07874
Putative FKBP12-rapamycin complex-associated protein; Belongs to the PI3/PI4-kinase family.
    
 0.962
PMG11_07331
Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.
    
 
 0.935
PMG11_02857
RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
    
 
 0.933
rvb1
RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
    
 
 0.922
PMG11_08342
Putative DNA repair protein RAD1.
   
 
 0.919
PMG11_08564
Putative Histone acetylase complex subunit Paf400; Belongs to the PI3/PI4-kinase family.
   
 
 0.877
PMG11_00292
Putative DEAD-box like helicase.
    
 
 0.818
Your Current Organism:
Penicillium brasilianum
NCBI taxonomy Id: 104259
Other names: ATCC 12072, CBS 253.55, FRR 3466, P. brasilianum, Penicillium sp. 028M, Penicillium sp. FKI-3368, QM 6947
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