node1 | node2 | node1 annotation | node2 annotation | score |
A0A074X671 | A0A074X6T1 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Pyruvate carboxyltransferase. | 0.870 |
A0A074X671 | A0A074X6X8 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.747 |
A0A074X671 | A0A074X7T9 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 3-ketoacyl-CoA thiolase-like protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.976 |
A0A074X671 | A0A074X8D2 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Putative nonspecific lipid-transfer protein, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. | 0.901 |
A0A074X671 | A0A074X9Y2 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Short chain dehydrogenase. | 0.870 |
A0A074X671 | A0A074XDW3 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Hydroxymethylglutaryl-CoA lyase. | 0.877 |
A0A074X671 | A0A074XWI0 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.979 |
A0A074X671 | A0A074XYB1 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Beta ketoadipyl CoA thiolase, TH2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.976 |
A0A074X671 | A0A074Y5M7 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.986 |
A0A074X671 | A0A074YIY2 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Sterol-binding-like protein. | 0.901 |
A0A074X6T1 | A0A074X671 | Pyruvate carboxyltransferase. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.870 |
A0A074X6T1 | A0A074X6X8 | Pyruvate carboxyltransferase. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.767 |
A0A074X6T1 | A0A074X7T9 | Pyruvate carboxyltransferase. | 3-ketoacyl-CoA thiolase-like protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.851 |
A0A074X6T1 | A0A074X8D2 | Pyruvate carboxyltransferase. | Putative nonspecific lipid-transfer protein, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. | 0.851 |
A0A074X6T1 | A0A074X9Y2 | Pyruvate carboxyltransferase. | Short chain dehydrogenase. | 0.839 |
A0A074X6T1 | A0A074XDW3 | Pyruvate carboxyltransferase. | Hydroxymethylglutaryl-CoA lyase. | 0.807 |
A0A074X6T1 | A0A074XWI0 | Pyruvate carboxyltransferase. | Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.851 |
A0A074X6T1 | A0A074XYB1 | Pyruvate carboxyltransferase. | Beta ketoadipyl CoA thiolase, TH2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.851 |
A0A074X6T1 | A0A074Y5M7 | Pyruvate carboxyltransferase. | Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.851 |
A0A074X6T1 | A0A074YIY2 | Pyruvate carboxyltransferase. | Sterol-binding-like protein. | 0.855 |