A0A074XEL7 protein (Aureobasidium pullulans)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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Coexpression

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[Homology]

Score

A0A074XEL7

BHLH domain-containing protein. (290 aa)

Predicted Functional Partners:

A0A074XV61

0.794

A0A074XZX3

0.794

A0A074XN36

0.775

A0A074YCC5

0.630

A0A074XI22

0.622

A0A074X5P9

0.466

A0A074XBI8

0.466

A0A074XJ16

0.466

A0A074XIT6

0.403

A0A074XRL0

0.403

Your Current Organism:

Aureobasidium pullulans

NCBI taxonomy Id: 1043002
Other names: A. pullulans EXF-150, Aureobasidium pullulans EXF-150, Aureobasidium pullulans var. pullulans EXF-150

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A074X5P9	A0A074XEL7	BHLH domain-containing protein.	BHLH domain-containing protein.	0.466
A0A074XBI8	A0A074XEL7	BHLH domain-containing protein.	BHLH domain-containing protein.	0.466
A0A074XEL7	A0A074X5P9	BHLH domain-containing protein.	BHLH domain-containing protein.	0.466
A0A074XEL7	A0A074XBI8	BHLH domain-containing protein.	BHLH domain-containing protein.	0.466
A0A074XEL7	A0A074XI22	BHLH domain-containing protein.	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.622
A0A074XEL7	A0A074XIT6	BHLH domain-containing protein.	Uncharacterized protein.	0.403
A0A074XEL7	A0A074XJ16	BHLH domain-containing protein.	BHLH domain-containing protein.	0.466
A0A074XEL7	A0A074XN36	BHLH domain-containing protein.	ARM repeat-containing protein.	0.775
A0A074XEL7	A0A074XRL0	BHLH domain-containing protein.	Uncharacterized protein.	0.403
A0A074XEL7	A0A074XV61	BHLH domain-containing protein.	SSD domain-containing protein.	0.794
A0A074XEL7	A0A074XZX3	BHLH domain-containing protein.	Multidrug efflux transporter AcrB transmembrane domain-containing protein.	0.794
A0A074XEL7	A0A074YCC5	BHLH domain-containing protein.	Uncharacterized protein.	0.630
A0A074XI22	A0A074XEL7	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	BHLH domain-containing protein.	0.622
A0A074XI22	A0A074XN36	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	ARM repeat-containing protein.	0.993
A0A074XIT6	A0A074XEL7	Uncharacterized protein.	BHLH domain-containing protein.	0.403
A0A074XJ16	A0A074XEL7	BHLH domain-containing protein.	BHLH domain-containing protein.	0.466
A0A074XN36	A0A074XEL7	ARM repeat-containing protein.	BHLH domain-containing protein.	0.775
A0A074XN36	A0A074XI22	ARM repeat-containing protein.	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.993
A0A074XRL0	A0A074XEL7	Uncharacterized protein.	BHLH domain-containing protein.	0.403
A0A074XV61	A0A074XEL7	SSD domain-containing protein.	BHLH domain-containing protein.	0.794

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

51

average node degree:

9.27

avg. local clustering coefficient:

0.927

expected number of edges:

10

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0055085

Transmembrane transport

11 of 553

0.96

1.13

4.11e-08

GO:0008643

Carbohydrate transport

3 of 41

1.53

0.75

0.0278

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0015144

Carbohydrate transmembrane transporter activity

3 of 20

1.84

0.99

0.0114

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005886

Plasma membrane

8 of 922

0.6

0.4

0.0173

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7220

Mixed, incl. Bacterial extracellular solute-binding protein, and glycerol-3-phosphate transmembrane transporter activity

11 of 37

2.14

7.5

1.63e-20

CL:7222

Mixed, incl. glycerol-3-phosphate transmembrane transporter activity, and ABC-type carbohydrate transporter activity

10 of 28

2.22

7.42

8.63e-19

CL:7262

MalK, OB fold domain, and ABC-type carbohydrate transporter activity

6 of 8

2.54

5.59

8.74e-12

CL:7223

Mixed, incl. glycerol-3-phosphate transmembrane transporter activity, and ABC-type carbohydrate transporter activity

4 of 20

1.97

2.28

1.65e-05

CL:7247

Mixed, incl. glycerol-3-phosphate transmembrane transport, and ABC-type carbohydrate transporter activity

3 of 8

2.24

1.99

0.00015

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02010

ABC transporters

11 of 326

1.19

1.85

1.17e-11

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0043190

ATP-binding cassette (ABC) transporter complex

7 of 68

1.68

2.86

1.21e-08

GOCC:0055052

ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

3 of 19

1.86

1.69

0.00032

GOCC:1902517

glycerol-3-phosphate-transporting ATPase complex

2 of 3

2.49

1.6

0.0011

GOCC:0005886

Plasma membrane

10 of 723

0.81

1.68e-06

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0813

Transport

9 of 279

1.17

1.56

6.24e-08

KW-1003

Cell membrane

7 of 329

0.99

0.94

0.00016

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00528

Binding-protein-dependent transport system inner membrane component

7 of 65

1.7

2.85

1.99e-08

PF13416

Bacterial extracellular solute-binding protein

3 of 15

1.97

1.35

0.0023

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000515

ABC transporter type 1, transmembrane domain MetI-like

7 of 66

1.69

2.72

5.79e-08

IPR035906

MetI-like superfamily

7 of 67

1.68

2.71

5.79e-08

IPR006059

Bacterial extracellular solute-binding protein

3 of 16

1.94

1.19

0.0047

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