A0A074Y784 protein (Aureobasidium pullulans)

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

A0A074Y784

Kelch repeat protein. (353 aa)

Predicted Functional Partners:

A0A074XM34

0.641

A0A074XCL2

0.594

A0A074X5Z8

0.587

A0A074XPD2

0.587

A0A074XYZ8

0.587

A0A074X5G5

0.575

A0A074X1K6

0.561

A0A074XKU5

0.561

A0A074Y4T8

0.561

A0A074XWU4

0.549

Your Current Organism:

Aureobasidium pullulans

NCBI taxonomy Id: 1043002
Other names: A. pullulans EXF-150, Aureobasidium pullulans EXF-150, Aureobasidium pullulans var. pullulans EXF-150

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A074X1K6	A0A074X5G5	Uncharacterized protein.	GTP binding protein-like protein.	0.814
A0A074X1K6	A0A074Y4T8	Uncharacterized protein.	DNA_pol_E_B domain-containing protein.	0.814
A0A074X1K6	A0A074Y784	Uncharacterized protein.	Kelch repeat protein.	0.561
A0A074X5G5	A0A074X1K6	GTP binding protein-like protein.	Uncharacterized protein.	0.814
A0A074X5G5	A0A074XKU5	GTP binding protein-like protein.	Uncharacterized protein.	0.814
A0A074X5G5	A0A074Y4T8	GTP binding protein-like protein.	DNA_pol_E_B domain-containing protein.	0.814
A0A074X5G5	A0A074Y784	GTP binding protein-like protein.	Kelch repeat protein.	0.575
A0A074X5Z8	A0A074XCL2	Helo_like_N domain-containing protein.	Ras-related protein-like protein.	0.790
A0A074X5Z8	A0A074XYZ8	Helo_like_N domain-containing protein.	AAA-domain-containing protein.	0.917
A0A074X5Z8	A0A074Y784	Helo_like_N domain-containing protein.	Kelch repeat protein.	0.587
A0A074XCL2	A0A074X5Z8	Ras-related protein-like protein.	Helo_like_N domain-containing protein.	0.790
A0A074XCL2	A0A074XPD2	Ras-related protein-like protein.	Vesicle-associated membrane protein 4.	0.790
A0A074XCL2	A0A074XYZ8	Ras-related protein-like protein.	AAA-domain-containing protein.	0.827
A0A074XCL2	A0A074Y784	Ras-related protein-like protein.	Kelch repeat protein.	0.594
A0A074XKU5	A0A074X5G5	Uncharacterized protein.	GTP binding protein-like protein.	0.814
A0A074XKU5	A0A074Y4T8	Uncharacterized protein.	DNA_pol_E_B domain-containing protein.	0.814
A0A074XKU5	A0A074Y784	Uncharacterized protein.	Kelch repeat protein.	0.561
A0A074XM34	A0A074XWU4	Protein phosphatase PP2A regulatory subunit A.	Serine/threonine-protein phosphatase.	0.999
A0A074XM34	A0A074Y784	Protein phosphatase PP2A regulatory subunit A.	Kelch repeat protein.	0.641
A0A074XPD2	A0A074XCL2	Vesicle-associated membrane protein 4.	Ras-related protein-like protein.	0.790

page 1 of 3

Network Stats

number of nodes:

6

number of edges:

13

average node degree:

4.33

avg. local clustering coefficient:

0.9

expected number of edges:

5

PPI enrichment p-value:

0.00201

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009168

Purine ribonucleoside monophosphate biosynthetic process

7 of 18

1.88

3.49

2.80e-09

GO:0006189

De novo IMP biosynthetic process

6 of 13

1.96

3.49

8.61e-09

GO:0009152

Purine ribonucleotide biosynthetic process

7 of 35

1.6

2.69

8.99e-09

GO:0009260

Ribonucleotide biosynthetic process

8 of 47

1.53

2.6

2.80e-09

GO:0044208

De novo AMP biosynthetic process

2 of 2

2.29

1.42

0.0022

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016879

Ligase activity, forming carbon-nitrogen bonds

5 of 35

1.45

1.4

0.00029

GO:0016742

Hydroxymethyl-, formyl- and related transferase activity

2 of 3

2.12

0.81

0.0319

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005829

Cytosol

5 of 98

1.0

0.75

0.0039

GO:0005622

Intracellular anatomical structure

11 of 680

0.5

0.43

0.00030

GO:0005737

Cytoplasm

9 of 557

0.5

0.38

0.0055

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:946

De novo IMP biosynthetic process

7 of 11

2.1

4.44

8.92e-11

CL:828

Cellular amino acid biosynthetic process, and Ribonucleoside monophosphate biosynthetic process

8 of 105

1.18

1.48

4.72e-07

CL:948

Phosphoribosylformylglycinamidine synthase activity, and PurE domain

2 of 6

1.82

0.78

0.0315

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00230

Purine metabolism

7 of 45

1.49

2.25

8.35e-08

map00670

One carbon pool by folate

2 of 6

1.82

0.93

0.0149

map00250

Alanine, aspartate and glutamate metabolism

3 of 25

1.37

0.84

0.0125

map01110

Biosynthesis of secondary metabolites

7 of 313

0.64

0.44

0.0125

map01100

Metabolic pathways

9 of 679

0.42

0.31

0.0160

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0658

Purine biosynthesis

5 of 11

1.95

2.81

6.58e-07

KW-0436

Ligase

5 of 56

1.25

1.16

0.00040

KW-0460

Magnesium

4 of 45

1.24

0.96

0.0030

KW-0315

Glutamine amidotransferase

2 of 12

1.52

0.64

0.0496

KW-0547

Nucleotide-binding

5 of 145

0.83

0.54

0.0162

(more ...)

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