A0A074YA49 protein (Aureobasidium pullulans)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

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[Homology]

Score

A0A074YA49

Uncharacterized protein. (240 aa)

Predicted Functional Partners:

A0A074X9M7

0.999

A0A074X9N1

0.999

A0A074XVE8

0.999

A0A074XWF6

0.999

A0A074XXM1

0.999

A0A074YCX3

0.999

A0A074YE93

0.999

A0A074YM61

0.999

A0A074XB46

0.998

A0A074XFU3

0.998

Your Current Organism:

Aureobasidium pullulans

NCBI taxonomy Id: 1043002
Other names: A. pullulans EXF-150, Aureobasidium pullulans EXF-150, Aureobasidium pullulans var. pullulans EXF-150

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A074X9M7	A0A074X9N1	Ribosomal protein S16, mitochondrial.	60S ribosomal protein L26.	0.999
A0A074X9M7	A0A074XB46	Ribosomal protein S16, mitochondrial.	Putative 40S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.	0.999
A0A074X9M7	A0A074XFU3	Ribosomal protein S16, mitochondrial.	Ribosomal_L18_c domain-containing protein.	0.998
A0A074X9M7	A0A074XVE8	Ribosomal protein S16, mitochondrial.	Uncharacterized protein.	0.999
A0A074X9M7	A0A074XWF6	Ribosomal protein S16, mitochondrial.	Uncharacterized protein.	0.999
A0A074X9M7	A0A074XXM1	Ribosomal protein S16, mitochondrial.	Ribosomal protein S6.	0.999
A0A074X9M7	A0A074YA49	Ribosomal protein S16, mitochondrial.	Uncharacterized protein.	0.999
A0A074X9M7	A0A074YCX3	Ribosomal protein S16, mitochondrial.	Mitochondrial ribosomal protein-like protein.	0.999
A0A074X9M7	A0A074YE93	Ribosomal protein S16, mitochondrial.	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	0.999
A0A074X9M7	A0A074YM61	Ribosomal protein S16, mitochondrial.	Ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family.	0.999
A0A074X9N1	A0A074X9M7	60S ribosomal protein L26.	Ribosomal protein S16, mitochondrial.	0.999
A0A074X9N1	A0A074XB46	60S ribosomal protein L26.	Putative 40S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.	0.999
A0A074X9N1	A0A074XFU3	60S ribosomal protein L26.	Ribosomal_L18_c domain-containing protein.	0.999
A0A074X9N1	A0A074XVE8	60S ribosomal protein L26.	Uncharacterized protein.	0.999
A0A074X9N1	A0A074XWF6	60S ribosomal protein L26.	Uncharacterized protein.	0.999
A0A074X9N1	A0A074XXM1	60S ribosomal protein L26.	Ribosomal protein S6.	0.999
A0A074X9N1	A0A074YA49	60S ribosomal protein L26.	Uncharacterized protein.	0.999
A0A074X9N1	A0A074YCX3	60S ribosomal protein L26.	Mitochondrial ribosomal protein-like protein.	0.999
A0A074X9N1	A0A074YE93	60S ribosomal protein L26.	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	0.999
A0A074X9N1	A0A074YM61	60S ribosomal protein L26.	Ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family.	0.999

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

37

average node degree:

6.73

avg. local clustering coefficient:

0.874

expected number of edges:

11

PPI enrichment p-value:

4.69e-10

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009116

Nucleoside metabolic process

6 of 12

2.19

3.97

4.21e-09

GO:0042278

Purine nucleoside metabolic process

3 of 3

2.49

2.1

0.00012

GO:0034655

Nucleobase-containing compound catabolic process

4 of 21

1.77

1.78

0.00013

GO:0009119

Ribonucleoside metabolic process

3 of 8

2.06

1.75

0.00036

GO:0055086

Nucleobase-containing small molecule metabolic process

8 of 130

1.28

1.71

3.20e-07

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016763

Pentosyltransferase activity

5 of 18

1.93

2.58

2.37e-06

GO:0106130

Purine phosphoribosyltransferase activity

2 of 2

2.49

1.07

0.0111

GO:0004731

Purine-nucleoside phosphorylase activity

2 of 2

2.49

1.07

0.0111

GO:0019239

Deaminase activity

2 of 8

1.89

0.69

0.0496

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

9 of 951

0.46

0.31

0.0334

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1517

Phosphoribosyl transferase domain, and Nucleobase transport

4 of 5

2.39

2.74

5.71e-06

CL:1105

UMP salvage, and Pyrimidine nucleoside metabolic process

3 of 6

2.19

1.77

0.00040

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00230

Purine metabolism

9 of 74

1.57

3.12

1.13e-11

map00240

Pyrimidine metabolism

6 of 48

1.58

2.35

2.80e-07

map00760

Nicotinate and nicotinamide metabolism

4 of 24

1.71

1.91

4.13e-05

map01110

Biosynthesis of secondary metabolites

6 of 348

0.72

0.51

0.0076

map01100

Metabolic pathways

11 of 986

0.54

0.47

4.13e-05

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-168249

Innate Immune System

3 of 21

1.64

1.42

0.00074

MAP-168256

Immune System

3 of 24

1.58

1.38

0.00074

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0660

Purine salvage

2 of 2

2.49

1.24

0.0052

KW-0328

Glycosyltransferase

5 of 78

1.29

1.17

0.00058

KW-0808

Transferase

6 of 367

0.7

0.43

0.0294

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00156

Phosphoribosyl transferase domain

3 of 6

2.19

1.59

0.00094

PF01048

Phosphorylase superfamily

2 of 3

2.31

0.91

0.0212

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR029057

Phosphoribosyltransferase-like

3 of 9

2.01

1.15

0.0063

IPR000836

Phosphoribosyltransferase domain

3 of 9

2.01

1.15

0.0063

IPR035994

Nucleoside phosphorylase superfamily

2 of 3

2.31

0.78

0.0365

IPR000845

Nucleoside phosphorylase domain

2 of 3

2.31

0.78

0.0365

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