node1 | node2 | node1 annotation | node2 annotation | score |
A0A074X671 | A0A074XG74 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. | 0.734 |
A0A074X671 | A0A074XJV1 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Putative farnesyl-diphosphate farnesyltransferase. | 0.934 |
A0A074X671 | A0A074XS73 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. | 0.894 |
A0A074X671 | A0A074XV03 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Lycopene beta-cyclase. | 0.867 |
A0A074X671 | A0A074XX92 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | ERG20 farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.813 |
A0A074X671 | A0A074XYR5 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.800 |
A0A074X671 | A0A074Y5Q6 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Squalene epoxidase. | 0.945 |
A0A074X671 | A0A074YMT1 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | IDI1, isopentenyl diphosphate:dimethylallyl diphosphate isomerase. | 0.907 |
A0A074XG74 | A0A074X671 | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.734 |
A0A074XG74 | A0A074XHA5 | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family. | 0.678 |
A0A074XG74 | A0A074XJV1 | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. | Putative farnesyl-diphosphate farnesyltransferase. | 0.952 |
A0A074XG74 | A0A074XQI6 | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.842 |
A0A074XG74 | A0A074XS73 | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. | Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. | 0.944 |
A0A074XG74 | A0A074XV03 | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. | Lycopene beta-cyclase. | 0.939 |
A0A074XG74 | A0A074XX92 | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. | ERG20 farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.943 |
A0A074XG74 | A0A074XYR5 | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.846 |
A0A074XG74 | A0A074Y5Q6 | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. | Squalene epoxidase. | 0.494 |
A0A074XG74 | A0A074YMT1 | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. | IDI1, isopentenyl diphosphate:dimethylallyl diphosphate isomerase. | 0.924 |
A0A074XHA5 | A0A074XG74 | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family. | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. | 0.678 |
A0A074XHA5 | A0A074XQI6 | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.441 |