STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A074WXB3P-loop containing nucleoside triphosphate hydrolase protein. (1225 aa)    
Predicted Functional Partners:
A0A074VIJ0
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.976
A0A074W1G4
DUF1767 domain-containing protein.
    
 0.975
A0A074WEW7
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
 0.971
A0A074VDS3
DNA repair protein rad10.
    
 0.964
A0A074WB51
DNA repair protein.
    
 0.953
A0A074VXG4
Polyubiquitin-tagged protein recognition complex, Npl4 component.
    
 0.947
A0A074W632
Uncharacterized protein.
   
 0.939
A0A074VK45
UvrD-helicase-domain-containing protein.
    
 
 0.918
A0A074VVG4
Ribonuclease H-like protein.
   
 0.906
A0A074W2U8
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.899
Your Current Organism:
Aureobasidium melanogenum
NCBI taxonomy Id: 1043003
Other names: A. melanogenum CBS 110374, Aureobasidium melanogenum CBS 110374, Aureobasidium pullulans var. melanogenum CBS 110374
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