STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
valSValine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner. (864 aa)    
Predicted Functional Partners:
glyQ
Glycine--tRNA ligase alpha subunit.
  
  
 0.971
leuS
Leucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
0.946
thrS
Threonine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
  
 0.909
ileS
Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
 
 
0.908
argS
Arginine--tRNA ligase.
  
  
 0.897
pheT
Phenylalanine--tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.893
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
  
  
 0.889
cysS
Cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.860
KJL22721.1
Hypothetical protein.
       0.853
hisS
Histidine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
 0.852
Your Current Organism:
Microbacterium foliorum
NCBI taxonomy Id: 104336
Other names: CIP 107137, DSM 12966, JCM 11569, LMG 19580, LMG:19580, M. foliorum, Microbacterium foliorum Behrendt et al. 2001, NBRC 103072, NRRL:B-24224, strain P 333/02
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