node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gltB_1 | glyA1 | RN50_02779 | RN50_00724 | Glutamate synthase [NADPH] large chain. | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.424 |
gltB_1 | lgt | RN50_02779 | RN50_02778 | Glutamate synthase [NADPH] large chain. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.718 |
gltB_1 | pabB | RN50_02779 | RN50_02293 | Glutamate synthase [NADPH] large chain. | Aminodeoxychorismate synthase component 1. | 0.412 |
gltB_1 | tdcB | RN50_02779 | RN50_03369 | Glutamate synthase [NADPH] large chain. | L-threonine dehydratase catabolic TdcB. | 0.861 |
gltB_1 | trpA | RN50_02779 | RN50_02777 | Glutamate synthase [NADPH] large chain. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.827 |
gltB_1 | trpB | RN50_02779 | RN50_02776 | Glutamate synthase [NADPH] large chain. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.934 |
gltB_1 | trpC | RN50_02779 | RN50_02775 | Glutamate synthase [NADPH] large chain. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.711 |
gltB_1 | trpD | RN50_02779 | RN50_01356 | Glutamate synthase [NADPH] large chain. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.407 |
gltB_1 | trpE | RN50_02779 | RN50_03097 | Glutamate synthase [NADPH] large chain. | Anthranilate synthase component 1. | 0.590 |
glyA1 | gltB_1 | RN50_00724 | RN50_02779 | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Glutamate synthase [NADPH] large chain. | 0.424 |
glyA1 | tdcB | RN50_00724 | RN50_03369 | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | L-threonine dehydratase catabolic TdcB. | 0.959 |
glyA1 | trpA | RN50_00724 | RN50_02777 | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.928 |
glyA1 | trpB | RN50_00724 | RN50_02776 | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.921 |
glyA1 | trpE | RN50_00724 | RN50_03097 | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Anthranilate synthase component 1. | 0.502 |
lgt | gltB_1 | RN50_02778 | RN50_02779 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Glutamate synthase [NADPH] large chain. | 0.718 |
lgt | pabB | RN50_02778 | RN50_02293 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Aminodeoxychorismate synthase component 1. | 0.400 |
lgt | trpA | RN50_02778 | RN50_02777 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.990 |
lgt | trpB | RN50_02778 | RN50_02776 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.990 |
lgt | trpC | RN50_02778 | RN50_02775 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.937 |
pabA | pabB | RN50_01658 | RN50_02293 | Aminodeoxychorismate/anthranilate synthase component 2. | Aminodeoxychorismate synthase component 1. | 0.999 |