node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EH31_00875 | EH31_01315 | EH31_00875 | EH31_01315 | Transketolase; Catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family. | Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.938 |
EH31_00875 | EH31_08425 | EH31_00875 | EH31_08425 | Transketolase; Catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family. | Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.581 |
EH31_00875 | EH31_15850 | EH31_00875 | EH31_15850 | Transketolase; Catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family. | Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. | 0.989 |
EH31_00875 | gapA | EH31_00875 | EH31_00880 | Transketolase; Catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family. | Glyceraldehyde-3-phosphate dehydrogenase; Required for glycolysis; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.992 |
EH31_00875 | glyA | EH31_00875 | EH31_01310 | Transketolase; Catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.495 |
EH31_00875 | prs | EH31_00875 | EH31_06370 | Transketolase; Catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family. | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.966 |
EH31_01315 | EH31_00875 | EH31_01315 | EH31_00875 | Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transketolase; Catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family. | 0.938 |
EH31_01315 | EH31_08425 | EH31_01315 | EH31_08425 | Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.583 |
EH31_01315 | EH31_15850 | EH31_01315 | EH31_15850 | Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. | 0.944 |
EH31_01315 | EH31_16835 | EH31_01315 | EH31_16835 | Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.593 |
EH31_01315 | gapA | EH31_01315 | EH31_00880 | Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glyceraldehyde-3-phosphate dehydrogenase; Required for glycolysis; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.642 |
EH31_01315 | glyA | EH31_01315 | EH31_01310 | Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.988 |
EH31_01315 | nrdR | EH31_01315 | EH31_01305 | Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | NrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.812 |
EH31_01315 | prs | EH31_01315 | EH31_06370 | Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.921 |
EH31_01315 | trmJ | EH31_01315 | EH31_01300 | Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | rRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.800 |
EH31_01315 | ubiG | EH31_01315 | EH31_11565 | Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.908 |
EH31_08425 | EH31_00875 | EH31_08425 | EH31_00875 | Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transketolase; Catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family. | 0.581 |
EH31_08425 | EH31_01315 | EH31_08425 | EH31_01315 | Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.583 |
EH31_08425 | EH31_15850 | EH31_08425 | EH31_15850 | Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. | 0.981 |
EH31_08425 | gapA | EH31_08425 | EH31_00880 | Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glyceraldehyde-3-phosphate dehydrogenase; Required for glycolysis; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.540 |