close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EH31_12295AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (600 aa)    
Predicted Functional Partners:
EH31_12680
AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.917
rplE
50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
    
 
 0.900
rplR
50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
    
 
 0.829
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.808
EH31_13570
Ankyrin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.763
EH31_12290
Gamma-glutamyltranspeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.628
EH31_01655
acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.590
EH31_02095
acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.590
EH31_05725
acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.590
EH31_05730
acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.590
Your Current Organism:
Erythrobacter longus
NCBI taxonomy Id: 1044
Other names: ATCC 33941, CIP 104268, DSM 6997, E. longus, IFO 14126, JCM 6170, NBRC 14126, strain OCh101
Server load: low (38%) [HD]