node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ciao1 | EAG_01441 | E2A1X3 | E2A8P5 | Probable cytosolic iron-sulfur protein assembly protein Ciao1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. | MMS19 nucleotide excision repair protein-like protein. | 0.992 |
Ciao1 | EAG_04509 | E2A1X3 | E2AAG2 | Probable cytosolic iron-sulfur protein assembly protein Ciao1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. | TFIIH basal transcription factor complex helicase subunit. | 0.771 |
Ciao1 | EAG_05027 | E2A1X3 | E2AK11 | Probable cytosolic iron-sulfur protein assembly protein Ciao1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. | Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...] | 0.693 |
Ciao1 | EAG_05579 | E2A1X3 | E2A1X2 | Probable cytosolic iron-sulfur protein assembly protein Ciao1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. | NIF3-like protein 1; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. | 0.821 |
Ciao1 | EAG_06695 | E2A1X3 | E2A591 | Probable cytosolic iron-sulfur protein assembly protein Ciao1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. | Cytosolic Fe-S cluster assembly factor NUBP1 homolog; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | 0.583 |
Ciao1 | EAG_07783 | E2A1X3 | E2ATX4 | Probable cytosolic iron-sulfur protein assembly protein Ciao1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. | Cytosolic Fe-S cluster assembly factor NUBP2 homolog; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. | 0.676 |
Ciao1 | EAG_11516 | E2A1X3 | E2AHN5 | Probable cytosolic iron-sulfur protein assembly protein Ciao1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. | UPF0195 protein CG7949. | 0.997 |
Ciao1 | EAG_13231 | E2A1X3 | E2AE87 | Probable cytosolic iron-sulfur protein assembly protein Ciao1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.577 |
Ciao1 | EAG_13302 | E2A1X3 | E1ZWU7 | Probable cytosolic iron-sulfur protein assembly protein Ciao1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. | Nuclear prelamin A recognition factor-like protein; Belongs to the NARF family. | 0.887 |
Ciao1 | EAG_14995 | E2A1X3 | E2ARP6 | Probable cytosolic iron-sulfur protein assembly protein Ciao1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. | UPF0195 protein CG30152. | 0.966 |
EAG_01441 | Ciao1 | E2A8P5 | E2A1X3 | MMS19 nucleotide excision repair protein-like protein. | Probable cytosolic iron-sulfur protein assembly protein Ciao1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. | 0.992 |
EAG_01441 | EAG_04509 | E2A8P5 | E2AAG2 | MMS19 nucleotide excision repair protein-like protein. | TFIIH basal transcription factor complex helicase subunit. | 0.968 |
EAG_01441 | EAG_05027 | E2A8P5 | E2AK11 | MMS19 nucleotide excision repair protein-like protein. | Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...] | 0.693 |
EAG_01441 | EAG_06695 | E2A8P5 | E2A591 | MMS19 nucleotide excision repair protein-like protein. | Cytosolic Fe-S cluster assembly factor NUBP1 homolog; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | 0.506 |
EAG_01441 | EAG_07783 | E2A8P5 | E2ATX4 | MMS19 nucleotide excision repair protein-like protein. | Cytosolic Fe-S cluster assembly factor NUBP2 homolog; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. | 0.506 |
EAG_01441 | EAG_11516 | E2A8P5 | E2AHN5 | MMS19 nucleotide excision repair protein-like protein. | UPF0195 protein CG7949. | 0.994 |
EAG_01441 | EAG_13231 | E2A8P5 | E2AE87 | MMS19 nucleotide excision repair protein-like protein. | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.514 |
EAG_01441 | EAG_13302 | E2A8P5 | E1ZWU7 | MMS19 nucleotide excision repair protein-like protein. | Nuclear prelamin A recognition factor-like protein; Belongs to the NARF family. | 0.800 |
EAG_01441 | EAG_14995 | E2A8P5 | E2ARP6 | MMS19 nucleotide excision repair protein-like protein. | UPF0195 protein CG30152. | 0.941 |
EAG_04509 | Ciao1 | E2AAG2 | E2A1X3 | TFIIH basal transcription factor complex helicase subunit. | Probable cytosolic iron-sulfur protein assembly protein Ciao1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. | 0.771 |