node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAG_00614 | EAG_02817 | E2A2L2 | E2ABV9 | Origin recognition complex subunit 2. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.998 |
EAG_00614 | EAG_02938 | E2A2L2 | E2AUA0 | Origin recognition complex subunit 2. | Protein chiffon. | 0.994 |
EAG_00614 | EAG_03024 | E2A2L2 | E2ARM0 | Origin recognition complex subunit 2. | Origin recognition complex subunit 3. | 0.999 |
EAG_00614 | EAG_08178 | E2A2L2 | E2A7N9 | Origin recognition complex subunit 2. | DNA helicase; Belongs to the MCM family. | 0.998 |
EAG_00614 | EAG_08989 | E2A2L2 | E2AUK1 | Origin recognition complex subunit 2. | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | 0.999 |
EAG_00614 | EAG_09213 | E2A2L2 | E2AKZ3 | Origin recognition complex subunit 2. | DNA helicase. | 0.999 |
EAG_00614 | EAG_14309 | E2A2L2 | E2A9C4 | Origin recognition complex subunit 2. | DNA helicase; Belongs to the MCM family. | 0.996 |
EAG_00614 | EAG_15328 | E2A2L2 | E2AHY1 | Origin recognition complex subunit 2. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Belongs to the MCM family. | 0.998 |
EAG_00614 | EAG_16079 | E2A2L2 | E2A2F9 | Origin recognition complex subunit 2. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.999 |
EAG_00614 | MCM7 | E2A2L2 | E2AL70 | Origin recognition complex subunit 2. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.996 |
EAG_02817 | EAG_00614 | E2ABV9 | E2A2L2 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Origin recognition complex subunit 2. | 0.998 |
EAG_02817 | EAG_02938 | E2ABV9 | E2AUA0 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Protein chiffon. | 0.893 |
EAG_02817 | EAG_03024 | E2ABV9 | E2ARM0 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Origin recognition complex subunit 3. | 0.999 |
EAG_02817 | EAG_08178 | E2ABV9 | E2A7N9 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.999 |
EAG_02817 | EAG_08989 | E2ABV9 | E2AUK1 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | 0.999 |
EAG_02817 | EAG_09213 | E2ABV9 | E2AKZ3 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase. | 0.999 |
EAG_02817 | EAG_14309 | E2ABV9 | E2A9C4 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.999 |
EAG_02817 | EAG_15328 | E2ABV9 | E2AHY1 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Belongs to the MCM family. | 0.999 |
EAG_02817 | EAG_16079 | E2ABV9 | E2A2F9 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.999 |
EAG_02817 | MCM7 | E2ABV9 | E2AL70 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |