EAG_15629 protein (Camponotus floridanus) - STRING interaction network

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Score

EAG_15629

Werner syndrome ATP-dependent helicase. (232 aa)

Predicted Functional Partners:

EAG_07871

0.797

EAG_11441

0.756

EAG_03464

0.715

EAG_14269

0.647

EAG_00988

0.633

EAG_15630

0.623

EAG_02503

0.612

EAG_15468

0.606

Fen1

0.595

EAG_13500

0.580

Your Current Organism:

Camponotus floridanus

NCBI taxonomy Id: 104421
Other names: C. floridanus, Camponotus floridana, Florida carpenter ant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EAG_00988	EAG_02503	E2ALX1	E2A6W4	DNA repair protein RAD52-like protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.840
EAG_00988	EAG_03464	E2ALX1	E2A0A1	DNA repair protein RAD52-like protein.	DNA2-like helicase.	0.893
EAG_00988	EAG_07871	E2ALX1	E2ATI8	DNA repair protein RAD52-like protein.	Exonuclease 1.	0.884
EAG_00988	EAG_11441	E2ALX1	E2A9M1	DNA repair protein RAD52-like protein.	Uncharacterized protein.	0.982
EAG_00988	EAG_13500	E2ALX1	E2A5S5	DNA repair protein RAD52-like protein.	Flap endonuclease GEN.	0.727
EAG_00988	EAG_14269	E2ALX1	E2A4D9	DNA repair protein RAD52-like protein.	ATP-dependent DNA helicase 2 subunit 1.	0.893
EAG_00988	EAG_15468	E2ALX1	E2AT96	DNA repair protein RAD52-like protein.	DNA-repair protein XRCC3.	0.919
EAG_00988	EAG_15629	E2ALX1	E2A2V4	DNA repair protein RAD52-like protein.	Werner syndrome ATP-dependent helicase.	0.633
EAG_00988	Fen1	E2ALX1	E2AQ57	DNA repair protein RAD52-like protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.882
EAG_02503	EAG_00988	E2A6W4	E2ALX1	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	DNA repair protein RAD52-like protein.	0.840
EAG_02503	EAG_03464	E2A6W4	E2A0A1	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	DNA2-like helicase.	0.863
EAG_02503	EAG_07871	E2A6W4	E2ATI8	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Exonuclease 1.	0.863
EAG_02503	EAG_11441	E2A6W4	E2A9M1	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Uncharacterized protein.	0.981
EAG_02503	EAG_13500	E2A6W4	E2A5S5	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Flap endonuclease GEN.	0.607
EAG_02503	EAG_14269	E2A6W4	E2A4D9	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	ATP-dependent DNA helicase 2 subunit 1.	0.582
EAG_02503	EAG_15468	E2A6W4	E2AT96	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	DNA-repair protein XRCC3.	0.852
EAG_02503	EAG_15629	E2A6W4	E2A2V4	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Werner syndrome ATP-dependent helicase.	0.612
EAG_02503	Fen1	E2A6W4	E2AQ57	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.707
EAG_03464	EAG_00988	E2A0A1	E2ALX1	DNA2-like helicase.	DNA repair protein RAD52-like protein.	0.893
EAG_03464	EAG_02503	E2A0A1	E2A6W4	DNA2-like helicase.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.863