node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCM7 | OBRU01_00326 | A0A0L7KNN6 | A0A0L7LVD0 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Minichromosome maintenance 5. | 0.998 |
MCM7 | OBRU01_03952 | A0A0L7KNN6 | A0A0L7LBP4 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Putative DNA replication licensing factor MCM4. | 0.996 |
MCM7 | OBRU01_03953 | A0A0L7KNN6 | A0A0L7LBY7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Disc proliferation abnormal; Belongs to the MCM family. | 0.999 |
MCM7 | OBRU01_05517 | A0A0L7KNN6 | A0A0L7L7D9 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.997 |
MCM7 | OBRU01_05518 | A0A0L7KNN6 | A0A0L7L7T2 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Putative DNA replication licensing factor Mcm2. | 0.999 |
MCM7 | OBRU01_07661 | A0A0L7KNN6 | A0A0L7LIF2 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | CDT1 domain-containing protein. | 0.998 |
MCM7 | OBRU01_08812 | A0A0L7KNN6 | A0A0L7LGS5 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA replication licensing factor Mcm6. | 0.997 |
MCM7 | OBRU01_13275 | A0A0L7KNN6 | A0A0L7L905 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA replication licensing factor MCM3. | 0.997 |
MCM7 | OBRU01_18840 | A0A0L7KNN6 | A0A0L7KYK0 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA replication licensing factor MCM3; Belongs to the MCM family. | 0.999 |
MCM7 | OBRU01_23855 | A0A0L7KNN6 | A0A0L7KN17 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.998 |
OBRU01_00326 | MCM7 | A0A0L7LVD0 | A0A0L7KNN6 | Minichromosome maintenance 5. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.998 |
OBRU01_00326 | OBRU01_03952 | A0A0L7LVD0 | A0A0L7LBP4 | Minichromosome maintenance 5. | Putative DNA replication licensing factor MCM4. | 0.998 |
OBRU01_00326 | OBRU01_03953 | A0A0L7LVD0 | A0A0L7LBY7 | Minichromosome maintenance 5. | Disc proliferation abnormal; Belongs to the MCM family. | 0.999 |
OBRU01_00326 | OBRU01_05517 | A0A0L7LVD0 | A0A0L7L7D9 | Minichromosome maintenance 5. | DNA helicase; Belongs to the MCM family. | 0.998 |
OBRU01_00326 | OBRU01_05518 | A0A0L7LVD0 | A0A0L7L7T2 | Minichromosome maintenance 5. | Putative DNA replication licensing factor Mcm2. | 0.998 |
OBRU01_00326 | OBRU01_07661 | A0A0L7LVD0 | A0A0L7LIF2 | Minichromosome maintenance 5. | CDT1 domain-containing protein. | 0.999 |
OBRU01_00326 | OBRU01_08812 | A0A0L7LVD0 | A0A0L7LGS5 | Minichromosome maintenance 5. | DNA replication licensing factor Mcm6. | 0.998 |
OBRU01_00326 | OBRU01_13275 | A0A0L7LVD0 | A0A0L7L905 | Minichromosome maintenance 5. | DNA replication licensing factor MCM3. | 0.998 |
OBRU01_00326 | OBRU01_18840 | A0A0L7LVD0 | A0A0L7KYK0 | Minichromosome maintenance 5. | DNA replication licensing factor MCM3; Belongs to the MCM family. | 0.998 |
OBRU01_00326 | OBRU01_23855 | A0A0L7LVD0 | A0A0L7KN17 | Minichromosome maintenance 5. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.999 |