node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFG96048.1 | SFG96082.1 | SAMN05216175_1228 | SAMN05216175_12210 | Alpha-ribazole phosphatase. | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.951 |
SFG96048.1 | SFG96116.1 | SAMN05216175_1228 | SAMN05216175_12212 | Alpha-ribazole phosphatase. | L-threonine O-3-phosphate decarboxylase. | 0.835 |
SFG96048.1 | SFG96148.1 | SAMN05216175_1228 | SAMN05216175_12214 | Alpha-ribazole phosphatase. | Cobyrinic acid a,c-diamide synthase. | 0.785 |
SFG96048.1 | SFG96165.1 | SAMN05216175_1228 | SAMN05216175_12215 | Alpha-ribazole phosphatase. | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.786 |
SFG96048.1 | SFG96184.1 | SAMN05216175_1228 | SAMN05216175_12216 | Alpha-ribazole phosphatase. | Hypothetical protein. | 0.642 |
SFG96048.1 | cobD | SAMN05216175_1228 | SAMN05216175_12213 | Alpha-ribazole phosphatase. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.895 |
SFG96048.1 | cobQ | SAMN05216175_1228 | SAMN05216175_12211 | Alpha-ribazole phosphatase. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.901 |
SFG96048.1 | cobS | SAMN05216175_1228 | SAMN05216175_1227 | Alpha-ribazole phosphatase. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.995 |
SFG96048.1 | cobT | SAMN05216175_1228 | SAMN05216175_1229 | Alpha-ribazole phosphatase. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.995 |
SFG96048.1 | cysG | SAMN05216175_1228 | SAMN05216175_110101 | Alpha-ribazole phosphatase. | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.561 |
SFG96082.1 | SFG96048.1 | SAMN05216175_12210 | SAMN05216175_1228 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Alpha-ribazole phosphatase. | 0.951 |
SFG96082.1 | SFG96116.1 | SAMN05216175_12210 | SAMN05216175_12212 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | L-threonine O-3-phosphate decarboxylase. | 0.994 |
SFG96082.1 | SFG96148.1 | SAMN05216175_12210 | SAMN05216175_12214 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Cobyrinic acid a,c-diamide synthase. | 0.992 |
SFG96082.1 | SFG96165.1 | SAMN05216175_12210 | SAMN05216175_12215 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.994 |
SFG96082.1 | SFG96184.1 | SAMN05216175_12210 | SAMN05216175_12216 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Hypothetical protein. | 0.834 |
SFG96082.1 | cobD | SAMN05216175_12210 | SAMN05216175_12213 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.997 |
SFG96082.1 | cobQ | SAMN05216175_12210 | SAMN05216175_12211 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.996 |
SFG96082.1 | cobS | SAMN05216175_12210 | SAMN05216175_1227 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.996 |
SFG96082.1 | cobT | SAMN05216175_12210 | SAMN05216175_1229 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.993 |
SFG96082.1 | cysG | SAMN05216175_12210 | SAMN05216175_110101 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.709 |