STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDI99443.1Probable phosphoglycerate mutase. (194 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
      0.891
SDI99484.1
poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
       0.801
gpmA
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 
 0.700
rnhA
Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
 
  0.668
SDJ92088.1
Cystathionine beta-synthase.
   
  0.666
SDI99523.1
NUDIX domain-containing protein.
    
  0.551
SDI99611.1
Hypothetical protein.
   
  0.496
SDI99564.1
Putative peptidoglycan lipid II flippase.
       0.473
SDJ12679.1
Probable phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family.
  
   
 0.410
Your Current Organism:
Arthrobacter cupressi
NCBI taxonomy Id: 1045773
Other names: A. cupressi, Arthrobacter cupressi Zhang et al. 2012, Arthrobacter sp. D48, CGMCC 1.10783, DSM 24664, strain D48
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