node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDF07808.1 | SDF08247.1 | SAMN04488121_101722 | SAMN04488121_101734 | methylmalonyl-CoA epimerase. | methylmalonyl-CoA mutase, C-terminal domain. | 0.996 |
SDF07808.1 | SDF16160.1 | SAMN04488121_101722 | SAMN04488121_101981 | methylmalonyl-CoA epimerase. | LAO/AO transport system kinase. | 0.904 |
SDF07808.1 | SDF55706.1 | SAMN04488121_101722 | SAMN04488121_102262 | methylmalonyl-CoA epimerase. | Acyl transferase domain-containing protein. | 0.775 |
SDF07808.1 | SDG43407.1 | SAMN04488121_101722 | SAMN04488121_104251 | methylmalonyl-CoA epimerase. | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | 0.664 |
SDF07808.1 | SDH13437.1 | SAMN04488121_101722 | SAMN04488121_10938 | methylmalonyl-CoA epimerase. | methylmalonyl-CoA mutase, N-terminal domain. | 0.968 |
SDF07808.1 | icmF | SAMN04488121_101722 | SAMN04488121_104344 | methylmalonyl-CoA epimerase. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.855 |
SDF07808.1 | mdh | SAMN04488121_101722 | SAMN04488121_106156 | methylmalonyl-CoA epimerase. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.421 |
SDF07808.1 | sucC | SAMN04488121_101722 | SAMN04488121_105278 | methylmalonyl-CoA epimerase. | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.450 |
SDF07808.1 | sucD | SAMN04488121_101722 | SAMN04488121_104192 | methylmalonyl-CoA epimerase. | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.432 |
SDF08247.1 | SDF07808.1 | SAMN04488121_101734 | SAMN04488121_101722 | methylmalonyl-CoA mutase, C-terminal domain. | methylmalonyl-CoA epimerase. | 0.996 |
SDF08247.1 | SDF16160.1 | SAMN04488121_101734 | SAMN04488121_101981 | methylmalonyl-CoA mutase, C-terminal domain. | LAO/AO transport system kinase. | 0.978 |
SDF08247.1 | SDF55706.1 | SAMN04488121_101734 | SAMN04488121_102262 | methylmalonyl-CoA mutase, C-terminal domain. | Acyl transferase domain-containing protein. | 0.915 |
SDF08247.1 | SDG43407.1 | SAMN04488121_101734 | SAMN04488121_104251 | methylmalonyl-CoA mutase, C-terminal domain. | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | 0.876 |
SDF08247.1 | SDH13437.1 | SAMN04488121_101734 | SAMN04488121_10938 | methylmalonyl-CoA mutase, C-terminal domain. | methylmalonyl-CoA mutase, N-terminal domain. | 0.999 |
SDF08247.1 | icmF | SAMN04488121_101734 | SAMN04488121_104344 | methylmalonyl-CoA mutase, C-terminal domain. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.998 |
SDF08247.1 | mdh | SAMN04488121_101734 | SAMN04488121_106156 | methylmalonyl-CoA mutase, C-terminal domain. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.857 |
SDF08247.1 | pckA | SAMN04488121_101734 | SAMN04488121_10149 | methylmalonyl-CoA mutase, C-terminal domain. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.858 |
SDF08247.1 | sucC | SAMN04488121_101734 | SAMN04488121_105278 | methylmalonyl-CoA mutase, C-terminal domain. | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.867 |
SDF08247.1 | sucD | SAMN04488121_101734 | SAMN04488121_104192 | methylmalonyl-CoA mutase, C-terminal domain. | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.882 |
SDF16160.1 | SDF07808.1 | SAMN04488121_101981 | SAMN04488121_101722 | LAO/AO transport system kinase. | methylmalonyl-CoA epimerase. | 0.904 |