STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDE89241.16-pyruvoyltetrahydropterin/6- carboxytetrahydropterin synthase. (137 aa)    
Predicted Functional Partners:
queE
Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
 
 0.992
folE
GTP cyclohydrolase I.
  
 
 0.968
SDE87338.1
Dinuclear metal center protein, YbgI/SA1388 family; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
    
 0.813
SDH14127.1
Dihydroneopterin aldolase.
    
 0.612
mqnB
Futalosine hydrolase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).
       0.606
mqnD
1,4-dihydroxy-6-naphthoate synthase; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.
       0.601
hisI
phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family.
     
 0.519
cysS
cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.518
SDH59587.1
Dihydropteroate synthase.
    
 0.504
SDE88683.1
NADP-dependent 3-hydroxy acid dehydrogenase YdfG; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
  0.457
Your Current Organism:
Chitinophaga filiformis
NCBI taxonomy Id: 104663
Other names: ATCC 29495, C. filiformis, CCUG 12809, CIP 106401, DSM 527, Flexibacter filiformis, IFO 15056, JCM 21160, Myxococcus filiformis, NBRC 15056, strain Fx e1 Reichenbach
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