node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDF23468.1 | SDF29566.1 | SAMN04488121_1011213 | SAMN04488121_1011402 | Glutamate synthase (NADH) large subunit. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.724 |
SDF23468.1 | SDF47755.1 | SAMN04488121_1011213 | SAMN04488121_10233 | Glutamate synthase (NADH) large subunit. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.873 |
SDF23468.1 | SDF55706.1 | SAMN04488121_1011213 | SAMN04488121_102262 | Glutamate synthase (NADH) large subunit. | Acyl transferase domain-containing protein. | 0.957 |
SDF23468.1 | SDF56003.1 | SAMN04488121_1011213 | SAMN04488121_102271 | Glutamate synthase (NADH) large subunit. | Phosphopantetheine attachment site. | 0.933 |
SDF23468.1 | SDG41922.1 | SAMN04488121_1011213 | SAMN04488121_104196 | Glutamate synthase (NADH) large subunit. | Allosteric NADP-dependent malic enzyme. | 0.738 |
SDF23468.1 | SDH29242.1 | SAMN04488121_1011213 | SAMN04488121_110185 | Glutamate synthase (NADH) large subunit. | Amino acid adenylation domain-containing protein; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.883 |
SDF23468.1 | pckA | SAMN04488121_1011213 | SAMN04488121_10149 | Glutamate synthase (NADH) large subunit. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.931 |
SDF29566.1 | SDF23468.1 | SAMN04488121_1011402 | SAMN04488121_1011213 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Glutamate synthase (NADH) large subunit. | 0.724 |
SDF29566.1 | SDF47680.1 | SAMN04488121_1011402 | SAMN04488121_10231 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Hypothetical protein. | 0.866 |
SDF29566.1 | SDF47755.1 | SAMN04488121_1011402 | SAMN04488121_10233 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.729 |
SDF29566.1 | SDF55706.1 | SAMN04488121_1011402 | SAMN04488121_102262 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Acyl transferase domain-containing protein. | 0.990 |
SDF29566.1 | SDF56003.1 | SAMN04488121_1011402 | SAMN04488121_102271 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Phosphopantetheine attachment site. | 0.915 |
SDF29566.1 | SDG41922.1 | SAMN04488121_1011402 | SAMN04488121_104196 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Allosteric NADP-dependent malic enzyme. | 0.940 |
SDF29566.1 | SDH29242.1 | SAMN04488121_1011402 | SAMN04488121_110185 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Amino acid adenylation domain-containing protein; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.955 |
SDF29566.1 | pckA | SAMN04488121_1011402 | SAMN04488121_10149 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.880 |
SDF47680.1 | SDF29566.1 | SAMN04488121_10231 | SAMN04488121_1011402 | Hypothetical protein. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.866 |
SDF47680.1 | SDF47721.1 | SAMN04488121_10231 | SAMN04488121_10232 | Hypothetical protein. | Hypothetical protein. | 0.497 |
SDF47680.1 | SDF47755.1 | SAMN04488121_10231 | SAMN04488121_10233 | Hypothetical protein. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.887 |
SDF47721.1 | SDF47680.1 | SAMN04488121_10232 | SAMN04488121_10231 | Hypothetical protein. | Hypothetical protein. | 0.497 |
SDF47721.1 | SDF47755.1 | SAMN04488121_10232 | SAMN04488121_10233 | Hypothetical protein. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.773 |