node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDF15611.1 | SDF28471.1 | SAMN04488121_101964 | SAMN04488121_1011371 | TIGR02757 family protein. | Exodeoxyribonuclease-3. | 0.926 |
SDF15611.1 | SDG87496.1 | SAMN04488121_101964 | SAMN04488121_10773 | TIGR02757 family protein. | Exodeoxyribonuclease-3. | 0.926 |
SDF15611.1 | polA | SAMN04488121_101964 | SAMN04488121_1011197 | TIGR02757 family protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.688 |
SDF15611.1 | ung | SAMN04488121_101964 | SAMN04488121_109241 | TIGR02757 family protein. | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.523 |
SDF19941.1 | SDF28471.1 | SAMN04488121_1011101 | SAMN04488121_1011371 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease-3. | 0.947 |
SDF19941.1 | SDG87496.1 | SAMN04488121_1011101 | SAMN04488121_10773 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease-3. | 0.947 |
SDF19941.1 | dut | SAMN04488121_1011101 | SAMN04488121_104220 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.926 |
SDF19941.1 | polA | SAMN04488121_1011101 | SAMN04488121_1011197 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.999 |
SDF19941.1 | ung | SAMN04488121_1011101 | SAMN04488121_109241 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.932 |
SDF28471.1 | SDF15611.1 | SAMN04488121_1011371 | SAMN04488121_101964 | Exodeoxyribonuclease-3. | TIGR02757 family protein. | 0.926 |
SDF28471.1 | SDF19941.1 | SAMN04488121_1011371 | SAMN04488121_1011101 | Exodeoxyribonuclease-3. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.947 |
SDF28471.1 | SDG87496.1 | SAMN04488121_1011371 | SAMN04488121_10773 | Exodeoxyribonuclease-3. | Exodeoxyribonuclease-3. | 0.853 |
SDF28471.1 | dut | SAMN04488121_1011371 | SAMN04488121_104220 | Exodeoxyribonuclease-3. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.430 |
SDF28471.1 | nth | SAMN04488121_1011371 | SAMN04488121_104246 | Exodeoxyribonuclease-3. | DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.992 |
SDF28471.1 | polA | SAMN04488121_1011371 | SAMN04488121_1011197 | Exodeoxyribonuclease-3. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.949 |
SDF28471.1 | ung | SAMN04488121_1011371 | SAMN04488121_109241 | Exodeoxyribonuclease-3. | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.921 |
SDG87496.1 | SDF15611.1 | SAMN04488121_10773 | SAMN04488121_101964 | Exodeoxyribonuclease-3. | TIGR02757 family protein. | 0.926 |
SDG87496.1 | SDF19941.1 | SAMN04488121_10773 | SAMN04488121_1011101 | Exodeoxyribonuclease-3. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.947 |
SDG87496.1 | SDF28471.1 | SAMN04488121_10773 | SAMN04488121_1011371 | Exodeoxyribonuclease-3. | Exodeoxyribonuclease-3. | 0.853 |
SDG87496.1 | dut | SAMN04488121_10773 | SAMN04488121_104220 | Exodeoxyribonuclease-3. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.430 |