STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (202 aa)    
Predicted Functional Partners:
mutM
DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
 
  
 0.988
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.891
SDW95618.1
Putative sporulation protein YtaF; Probably functions as a manganese efflux pump.
  
    0.871
SDW38007.1
Iturin family lipopeptide synthetase B/fengycin family lipopeptide synthetase D/tyrocidine synthetase-3.
  
 
 0.858
SDW03816.1
Amino acid adenylation domain-containing protein.
    
 0.857
SDX35788.1
Thioester reductase domain-containing protein.
    
 0.857
SDW95534.1
Soluble lytic murein transglycosylase.
  
    0.839
SDW03763.1
Acyl transferase domain-containing protein.
    
 0.809
acpS
Holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
    
 0.802
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.790
Your Current Organism:
Marininema mesophilum
NCBI taxonomy Id: 1048340
Other names: CCTCC AA 2011006, DSM 45610, M. mesophilum, Marininema mesophilum Li et al. 2012, SCSIO 10219, Thermoactinomycetaceae bacterium SCSIO 10219
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