EL17_00720 protein (Anditalea andensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

EL17_00720

Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (92 aa)

Predicted Functional Partners:

EL17_00725

0.932

EL17_09900

0.735

EL17_24215

0.658

EL17_00980

0.489

EL17_00730

0.413

Your Current Organism:

Anditalea andensis

NCBI taxonomy Id: 1048983
Other names: A. andensis, CICC 10485, Cytophagaceae bacterium ANESC-S, NCCB 100412, strain ANESC-S

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

Network Stats

number of nodes:

3

number of edges:

2

average node degree:

1.33

avg. local clustering coefficient:

0.667

expected number of edges:

2

PPI enrichment p-value:

0.527

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006641

Triglyceride metabolic process

5 of 17

2.65

4.41

4.08e-09

GO:0046486

Glycerolipid metabolic process

7 of 152

1.85

3.36

4.08e-09

GO:0044255

Cellular lipid metabolic process

9 of 558

1.39

2.21

4.08e-09

GO:0090407

Organophosphate biosynthetic process

6 of 321

1.45

1.77

1.04e-05

GO:0046167

glycerol-3-phosphate biosynthetic process

2 of 2

3.18

1.77

0.00063

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003841

1-acylglycerol-3-phosphate O-acyltransferase activity

3 of 4

3.06

2.78

8.68e-06

GO:0008374

O-acyltransferase activity

4 of 31

2.29

2.61

8.68e-06

GO:0004370

Glycerol kinase activity

2 of 2

3.18

1.76

0.00066

GO:0008195

Phosphatidate phosphatase activity

2 of 5

2.79

1.55

0.0015

GO:0016740

Transferase activity

6 of 1392

0.82

0.52

0.0177

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005811

Lipid droplet

3 of 46

2.0

1.29

0.0032

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:14149

Phosphate acyltransferases, and glycerol-3-phosphate dehydrogenase complex

6 of 10

2.96

6.92

1.05e-13

CL:14113

Glycerophospholipid metabolism, and O-acyltransferase activity

8 of 68

2.25

5.98

4.67e-14

CL:14114

Glycerophospholipid metabolism

7 of 46

2.37

5.89

4.01e-13

CL:14153

Phosphate acyltransferases

4 of 5

3.09

4.57

4.25e-09

CL:2867

Alditol phosphate metabolic process, and Major intrinsic protein, conserved site

2 of 5

2.79

1.44

0.0024

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00561

Glycerolipid metabolism

9 of 99

2.14

6.46

1.12e-16

map00564

Glycerophospholipid metabolism

8 of 152

1.9

4.53

7.07e-13

map00565

Ether lipid metabolism

3 of 38

2.08

2.05

8.48e-05

map01110

Biosynthesis of secondary metabolites

7 of 1129

0.98

0.94

8.48e-05

map01100

Metabolic pathways

9 of 3880

0.55

0.43

0.0020

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-75109

Triglyceride biosynthesis

3 of 6

2.88

2.61

1.68e-05

MAP-8979227

Triglyceride metabolism

3 of 8

2.76

2.59

1.68e-05

MAP-1483206

Glycerophospholipid biosynthesis

4 of 92

1.82

1.87

9.46e-05

MAP-1483257

Phospholipid metabolism

4 of 122

1.7

1.68

0.00018

MAP-1482801

Acyl chain remodelling of PS

2 of 11

2.44

1.25

0.0049

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005811

Lipid droplet

4 of 37

2.22

2.53

1.03e-05

GOCC:0005783

Endoplasmic reticulum

4 of 311

1.29

0.85

0.0093

GOCC:0012505

Endomembrane system

5 of 831

0.96

0.58

0.0224

GOCC:0043229

Intracellular organelle

11 of 4988

0.53

0.43

0.00084

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02782

FGGY family of carbohydrate kinases, C-terminal domain

2 of 4

2.88

1.21

0.0066

PF00370

FGGY family of carbohydrate kinases, N-terminal domain

2 of 4

2.88

1.21

0.0066

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR018483

Carbohydrate kinase, FGGY, conserved site

2 of 2

3.18

1.19

0.0073

IPR005999

Glycerol kinase

2 of 2

3.18

1.19

0.0073

IPR018485

Carbohydrate kinase, FGGY, C-terminal

2 of 4

2.88

1.18

0.0073

IPR018484

Carbohydrate kinase, FGGY, N-terminal

2 of 4

2.88

1.18

0.0073

IPR002123

Phospholipid/glycerol acyltransferase

2 of 6

2.71

1.18

0.0073

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00563

Phosphate acyltransferases

3 of 7

2.82

2.75

8.82e-06

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (22%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Fusion

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About

node1	node2	node1 annotation	node2 annotation	score
EL17_00720	EL17_00725	Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.932
EL17_00720	EL17_00730	Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.413
EL17_00720	EL17_00980	Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.489
EL17_00720	EL17_09900	Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.735
EL17_00720	EL17_24215	Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.658
EL17_00725	EL17_00720	Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.932
EL17_00725	EL17_00730	Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.450
EL17_00725	EL17_00980	Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.517
EL17_00730	EL17_00720	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.413
EL17_00730	EL17_00725	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.450
EL17_00980	EL17_00720	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.489
EL17_00980	EL17_00725	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.517
EL17_09900	EL17_00720	Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.735
EL17_24215	EL17_00720	Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.658