STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EL17_07545Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)    
Predicted Functional Partners:
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.799
EL17_06950
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.752
EL17_10610
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.752
EL17_03565
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.741
EL17_03880
4-phosphopantetheinyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the P-Pant transferase superfamily.
  
     0.738
EL17_15910
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.727
EL17_05415
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.722
EL17_05425
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.715
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.712
EL17_04070
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.696
Your Current Organism:
Anditalea andensis
NCBI taxonomy Id: 1048983
Other names: A. andensis, CICC 10485, Cytophagaceae bacterium ANESC-S, NCCB 100412, strain ANESC-S
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.