STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EL17_19210Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)    
Predicted Functional Partners:
EL17_07820
DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.908
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.908
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
    
 
 0.778
EL17_03670
ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.702
EL17_05475
ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.702
EL17_15480
ATP-dependent DNA helicase RecQ; Functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.702
EL17_01390
ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.650
EL17_22910
ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single strand break in duplex DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.628
EL17_12350
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.606
EL17_14510
3'-5' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.538
Your Current Organism:
Anditalea andensis
NCBI taxonomy Id: 1048983
Other names: A. andensis, CICC 10485, Cytophagaceae bacterium ANESC-S, NCCB 100412, strain ANESC-S
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.