Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hiuH5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (108 aa)    
Predicted Functional Partners:
uao
Uric acid degradation bifunctional protein.
 
 0.999
uox
Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
 
 
 0.998
uacT_1
Uric acid transporter UacT.
 
  
 0.944
AMY53833.1
Hypothetical protein.
 
 
 0.938
guaD_2
Guanine deaminase.
 
  
 0.797
AMY52988.1
8-oxoguanine deaminase.
 
  
 0.787
alc
Allantoicase; Belongs to the allantoicase family.
 
  
 0.759
AMY55507.1
Hypothetical protein; Belongs to the HpcH/HpaI aldolase family.
 
     0.713
pgdA
Peptidoglycan deacetylase.
 
    0.703
uacT_2
Uric acid transporter UacT.
 
  
 0.650
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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