exoA protein (Rhodococcus fascians D188) - STRING interaction network

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Score

exoA

Exodeoxyribonuclease. (278 aa)

Predicted Functional Partners:

nth

0.970

xthA

0.927

mutY

0.859

bmrR_1

0.827

dnaN

0.792

yidC_1

0.776

AMY55411.1

0.770

alkA_2

0.768

end

0.754

trpS

0.735

Your Current Organism:

Rhodococcus fascians D188

NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMY55411.1	exoA	A3L23_04102	A3L23_00141	Putative RNA pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family.	Exodeoxyribonuclease.	0.770
AMY55411.1	xthA	A3L23_04102	A3L23_02663	Putative RNA pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family.	Exodeoxyribonuclease III.	0.770
alkA_2	bmrR_1	A3L23_03029	A3L23_00178	Putative bifunctional transcriptional activator/DNA repair enzyme AlkA.	Multidrug-efflux transporter 1 regulator.	0.416
alkA_2	end	A3L23_03029	A3L23_01584	Putative bifunctional transcriptional activator/DNA repair enzyme AlkA.	Putative endonuclease 4.	0.490
alkA_2	exoA	A3L23_03029	A3L23_00141	Putative bifunctional transcriptional activator/DNA repair enzyme AlkA.	Exodeoxyribonuclease.	0.768
alkA_2	mutY	A3L23_03029	A3L23_02527	Putative bifunctional transcriptional activator/DNA repair enzyme AlkA.	A/G-specific adenine glycosylase.	0.499
alkA_2	nth	A3L23_03029	A3L23_02394	Putative bifunctional transcriptional activator/DNA repair enzyme AlkA.	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.588
alkA_2	xthA	A3L23_03029	A3L23_02663	Putative bifunctional transcriptional activator/DNA repair enzyme AlkA.	Exodeoxyribonuclease III.	0.768
bmrR_1	alkA_2	A3L23_00178	A3L23_03029	Multidrug-efflux transporter 1 regulator.	Putative bifunctional transcriptional activator/DNA repair enzyme AlkA.	0.416
bmrR_1	exoA	A3L23_00178	A3L23_00141	Multidrug-efflux transporter 1 regulator.	Exodeoxyribonuclease.	0.827
bmrR_1	mutY	A3L23_00178	A3L23_02527	Multidrug-efflux transporter 1 regulator.	A/G-specific adenine glycosylase.	0.739
bmrR_1	xthA	A3L23_00178	A3L23_02663	Multidrug-efflux transporter 1 regulator.	Exodeoxyribonuclease III.	0.828
dnaN	exoA	A3L23_01820	A3L23_00141	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Exodeoxyribonuclease.	0.792
dnaN	mutY	A3L23_01820	A3L23_02527	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	A/G-specific adenine glycosylase.	0.729
dnaN	xthA	A3L23_01820	A3L23_02663	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Exodeoxyribonuclease III.	0.792
dnaN	yidC_1	A3L23_01820	A3L23_00142	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Membrane protein insertase YidC.	0.457
end	alkA_2	A3L23_01584	A3L23_03029	Putative endonuclease 4.	Putative bifunctional transcriptional activator/DNA repair enzyme AlkA.	0.490
end	exoA	A3L23_01584	A3L23_00141	Putative endonuclease 4.	Exodeoxyribonuclease.	0.754
end	nth	A3L23_01584	A3L23_02394	Putative endonuclease 4.	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.810
end	xthA	A3L23_01584	A3L23_02663	Putative endonuclease 4.	Exodeoxyribonuclease III.	0.828