Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
Experiments
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[Homology]
Score
dnaE2Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1091 aa)    
Predicted Functional Partners:
AMY51537.1
Hypothetical protein.
 
  
 0.919
dinB_1
DNA polymerase IV.
 
  
 0.912
AMY55083.1
Hypothetical protein.
  
 
 0.847
dnaN
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.804
ssb_1
Single-stranded DNA-binding protein.
 
 
 
 0.746
dnaX_1
DNA polymerase III subunit gamma/tau.
  
 
 0.717
dnaX_2
DNA polymerase III subunit gamma/tau.
  
 
 0.717
dnaQ
DNA polymerase III subunit epsilon.
   
 
 0.713
bmrR_1
Multidrug-efflux transporter 1 regulator.
    
 
 0.706
ssb_2
Single-stranded DNA-binding protein.
   
 
 0.704
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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