Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sigD_1ECF RNA polymerase sigma factor SigD; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa)    
Predicted Functional Partners:
AMY51549.1
Hypothetical protein.
 
     0.906
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.799
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.799
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.636
ripA_2
Peptidoglycan endopeptidase RipA.
  
  
 0.603
sigE
ECF RNA polymerase sigma factor SigE; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.588
AMY53930.1
Hypothetical protein.
   
    0.585
AMY51551.1
Hypothetical protein.
       0.549
sigL
ECF RNA polymerase sigma factor SigL; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.518
lytC_2
N-acetylmuramoyl-L-alanine amidase LytC.
  
    0.508
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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