Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sad_1Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (483 aa)    
Predicted Functional Partners:
gabT_1
4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.993
davT
5-aminovalerate aminotransferase DavT; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.928
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.925
kgd
Multifunctional 2-oxoglutarate metabolism enzyme.
  
 0.920
garL
5-keto-4-deoxy-D-glucarate aldolase; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.911
gltA2
Citrate synthase 1; Belongs to the citrate synthase family.
  
 0.881
citA
Putative citrate synthase 2; Belongs to the citrate synthase family.
  
 0.881
pckG
Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
   
 
 0.812
mqo
Putative malate:quinone oxidoreductase.
   
 
 0.812
cfiB_1
2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.810
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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