| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMY51435.1 | csd_1 | A3L23_00074 | A3L23_00523 | Putative SufE-like protein. | Putative cysteine desulfurase; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. | 0.596 |
| AMY51435.1 | sufB | A3L23_00074 | A3L23_04333 | Putative SufE-like protein. | FeS cluster assembly protein SufB. | 0.481 |
| AMY51435.1 | sufC | A3L23_00074 | A3L23_04331 | Putative SufE-like protein. | Vegetative protein 296. | 0.732 |
| AMY51435.1 | sufD | A3L23_00074 | A3L23_04332 | Putative SufE-like protein. | FeS cluster assembly protein SufD. | 0.543 |
| AMY54310.1 | csd_1 | A3L23_02977 | A3L23_00523 | Hypothetical protein. | Putative cysteine desulfurase; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. | 0.602 |
| csd_1 | AMY51435.1 | A3L23_00523 | A3L23_00074 | Putative cysteine desulfurase; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. | Putative SufE-like protein. | 0.596 |
| csd_1 | AMY54310.1 | A3L23_00523 | A3L23_02977 | Putative cysteine desulfurase; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. | Hypothetical protein. | 0.602 |
| csd_1 | egtA | A3L23_00523 | A3L23_00522 | Putative cysteine desulfurase; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. | Glutamate--cysteine ligase GshA; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | 0.710 |
| csd_1 | egtB | A3L23_00523 | A3L23_00521 | Putative cysteine desulfurase; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. | Iron(II)-dependent oxidoreductase EgtB; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.727 |
| csd_1 | egtC | A3L23_00523 | A3L23_00520 | Putative cysteine desulfurase; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. | Amidohydrolase EgtC; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | 0.672 |
| csd_1 | egtD | A3L23_00523 | A3L23_00519 | Putative cysteine desulfurase; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. | Histidine-specific methyltransferase EgtD; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. | 0.878 |
| csd_1 | iscU | A3L23_00523 | A3L23_04329 | Putative cysteine desulfurase; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. | Iron-sulfur cluster assembly scaffold protein IscU. | 0.970 |
| csd_1 | sufB | A3L23_00523 | A3L23_04333 | Putative cysteine desulfurase; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. | FeS cluster assembly protein SufB. | 0.843 |
| csd_1 | sufC | A3L23_00523 | A3L23_04331 | Putative cysteine desulfurase; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. | Vegetative protein 296. | 0.886 |
| csd_1 | sufD | A3L23_00523 | A3L23_04332 | Putative cysteine desulfurase; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. | FeS cluster assembly protein SufD. | 0.817 |
| egtA | csd_1 | A3L23_00522 | A3L23_00523 | Glutamate--cysteine ligase GshA; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | Putative cysteine desulfurase; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. | 0.710 |
| egtA | egtB | A3L23_00522 | A3L23_00521 | Glutamate--cysteine ligase GshA; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | Iron(II)-dependent oxidoreductase EgtB; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.989 |
| egtA | egtC | A3L23_00522 | A3L23_00520 | Glutamate--cysteine ligase GshA; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | Amidohydrolase EgtC; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | 0.980 |
| egtA | egtD | A3L23_00522 | A3L23_00519 | Glutamate--cysteine ligase GshA; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | Histidine-specific methyltransferase EgtD; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. | 0.979 |
| egtB | csd_1 | A3L23_00521 | A3L23_00523 | Iron(II)-dependent oxidoreductase EgtB; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Putative cysteine desulfurase; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. | 0.727 |