Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
amt_1Ammonia channel. (444 aa)    
Predicted Functional Partners:
glnB
Nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 0.997
gltB_2
Glutamate synthase [NADPH] large chain.
 
  
 0.851
gltB_1
Glutamate synthase [NADPH] large chain.
 
  
 0.850
echA6
Putative enoyl-CoA hydratase echA6; Belongs to the enoyl-CoA hydratase/isomerase family.
       0.773
glnD
Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
 
   
 0.575
glnA_3
Glutamine synthetase 1.
  
  
 0.573
glnA_2
Putative glutamine synthetase 2.
  
  
 0.569
czcO_1
Putative oxidoreductase CzcO.
  
  
 0.561
ureA
Urease subunit alpha; Belongs to the urease beta subunit family.
  
  
 0.560
aspA
Aspartate ammonia-lyase.
   
  
 0.453
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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