Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (373 aa)    
Predicted Functional Partners:
serA
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 0.980
serB_2
Phosphoserine phosphatase.
  
 
 0.974
thrC
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
   
 0.951
sbnA
Putative siderophore biosynthesis protein SbnA.
  
 
 0.918
citA
Putative citrate synthase 2; Belongs to the citrate synthase family.
 
 
 0.889
pheA
Prephenate dehydratase.
  
  
 0.743
hprA_1
Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.710
hprA_2
Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.710
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
  
 0.705
AMY53032.1
Putative 2-hydroxyacid dehydrogenase.
  
 
 0.703
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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