Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
pbuGGuanine/hypoxanthine permease PbuG. (481 aa)    
Predicted Functional Partners:
AMY52076.1
Hypothetical protein.
 
     0.799
rutG_2
Putative pyrimidine permease RutG.
 
  
 0.778
rutG_1
Putative pyrimidine permease RutG.
 
  
 0.755
AMY52074.1
Putative HTH-type transcriptional regulator.
     
 0.752
purE
N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
  
 0.643
purK
N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
  
    0.606
guaA_1
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.591
uacT_1
Uric acid transporter UacT.
 
  
 0.568
purD
Phosphoribosylamine--glycine ligase; Belongs to the GARS family.
  
  
 0.557
purH
Bifunctional purine biosynthesis protein PurH.
  
  
 0.537
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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