Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trxA_1Thioredoxin. (137 aa)    
Predicted Functional Partners:
resA_1
Thiol-disulfide oxidoreductase ResA.
  
 
 0.899
resA_2
Thiol-disulfide oxidoreductase ResA.
  
 
 0.899
AMY52121.1
Hypothetical protein.
 
     0.895
msrB
Peptide methionine sulfoxide reductase MsrB.
   
 
 0.801
msrA
Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 
 0.797
AMY52123.1
Hypothetical protein.
 
     0.556
phoP
Alkaline phosphatase synthesis transcriptional regulatory protein PhoP.
  
  
 0.543
mshD_2
Mycothiol acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
       0.533
pknE_2
Serine/threonine-protein kinase PknE.
 
 
 0.525
nhaA_2
Na(+)/H(+) antiporter NhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
  
 
 0.473
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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