Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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[Homology]
Score
fadMProline dehydrogenase 1. (314 aa)    
Predicted Functional Partners:
rocA1
1-pyrroline-5-carboxylate dehydrogenase 1.
 
 0.993
pip_1
Proline iminopeptidase; Belongs to the peptidase S33 family.
     
 0.960
pip_2
Proline iminopeptidase; Belongs to the peptidase S33 family.
     
 0.960
proC_2
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 0.956
AMY52213.1
Hypothetical protein.
 
   
 0.726
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.647
AMY53735.1
Serine protease; Belongs to the peptidase S1B family.
      
 0.631
ald_1
3-succinoylsemialdehyde-pyridine dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 
 0.587
AMY52216.1
Hypothetical protein.
       0.584
sad_1
Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 
 0.566
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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