Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ald_2Alanine dehydrogenase; Belongs to the AlaDH/PNT family. (360 aa)    
Predicted Functional Partners:
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
 
 0.926
aspC_2
Putative aspartate aminotransferase.
     
 0.904
aspC_3
Putative aspartate aminotransferase.
     
 0.904
pntB
NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
      0.904
lysN_1
2-aminoadipate transaminase.
    
 0.900
lysN_4
2-aminoadipate transaminase.
    
 0.900
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.826
poxB
Pyruvate dehydrogenase; Belongs to the TPP enzyme family.
     
 0.815
ppdK
Pyruvate, phosphate dikinase.
    
 0.812
AMY54468.1
NAD-dependent malic enzyme.
    
  0.807
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
Server load: low (28%) [HD]