Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lipF_2Carboxylesterase LipF. (335 aa)    
Predicted Functional Partners:
AMY52475.1
Hypothetical protein.
 
     0.884
ephD_1
Putative oxidoreductase EphD; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
     0.880
AMY52474.1
Baeyer-Villiger monooxygenase.
  
 0.872
AMY52473.1
Hypothetical protein.
 
     0.760
hmp_2
3-ketosteroid-9-alpha-hydroxylase reductase subunit.
 
 
   0.723
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
      
 0.647
petC1
Cytochrome b6-f complex iron-sulfur subunit 1.
  
 
 0.640
alkB_1
Alkane 1-monooxygenase.
      
 0.618
nuoI
NADH-quinone oxidoreductase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
 0.594
ppsA
Phthiocerol synthesis polyketide synthase type I PpsA.
  
 
 0.549
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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