Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
edaKHG/KDPG aldolase. (219 aa)    
Predicted Functional Partners:
kdgK_2
2-dehydro-3-deoxygluconokinase.
 
 
 0.987
kdgK_3
2-dehydro-3-deoxygluconokinase.
 
 
 0.971
kdgA
KHG/KDPG aldolase.
  
  
 
0.922
kgd
Multifunctional 2-oxoglutarate metabolism enzyme.
     
 0.916
aceA
Isocitrate lyase.
     
 0.907
AMY53577.1
Putative FAD-linked oxidoreductase.
   
 
 0.906
AMY54382.1
Putative FAD-linked oxidoreductase.
   
 
 0.906
AMY54560.1
Putative FAD-linked oxidoreductase.
   
 
 0.906
AMY51987.1
Putative 2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
  0.904
glcB_2
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
     
 0.903
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
Server load: low (12%) [HD]