Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMY52872.1Hypothetical protein; Multifunctional non-homologous end joining protein LigD. (361 aa)    
Predicted Functional Partners:
ligC
DNA ligase C1.
   
 0.994
ku
Hypothetical protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.884
ligB
DNA ligase B.
   
 0.669
AMY52874.1
Hypothetical protein.
       0.572
stp_3
Multidrug resistance protein Stp; Belongs to the major facilitator superfamily.
       0.546
polX
DNA polymerase/3'-5' exonuclease PolX.
 
   
 0.460
fpg2
Putative formamidopyrimidine-DNA glycosylase-like protein; Belongs to the FPG family.
 
   
 0.419
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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