Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
leuA_22-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (155 aa)    
Predicted Functional Partners:
AMY54101.1
Hypothetical protein.
  
     0.673
accC_3
Biotin carboxylase.
  
 
 0.673
AMY53374.1
Hypothetical protein.
  
     0.672
embB
Putative arabinosyltransferase B.
  
   
 0.626
hicd
Homoisocitrate dehydrogenase.
  
 
 0.625
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
  
 
 0.625
embC_1
Putative arabinosyltransferase C.
  
   
 0.620
embC_2
Putative arabinosyltransferase C.
  
   
 0.617
lpqB
Lipoprotein LpqB.
  
     0.608
hacA
Homoaconitase large subunit.
  
  
 0.599
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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