| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| antA | dmg_1 | A3L23_02130 | A3L23_02135 | Anthranilate 1,2-dioxygenase large subunit. | Dimethylglycine oxidase; Belongs to the GcvT family. | 0.833 |
| antA | soxA | A3L23_02130 | A3L23_02141 | Anthranilate 1,2-dioxygenase large subunit. | Sarcosine oxidase subunit alpha. | 0.735 |
| antA | soxB | A3L23_02130 | A3L23_02143 | Anthranilate 1,2-dioxygenase large subunit. | Sarcosine oxidase subunit beta. | 0.673 |
| antA | soxD | A3L23_02130 | A3L23_02142 | Anthranilate 1,2-dioxygenase large subunit. | Sarcosine oxidase subunit delta. | 0.709 |
| antA | soxG | A3L23_02130 | A3L23_02140 | Anthranilate 1,2-dioxygenase large subunit. | Sarcosine oxidase subunit gamma. | 0.693 |
| dmg_1 | antA | A3L23_02135 | A3L23_02130 | Dimethylglycine oxidase; Belongs to the GcvT family. | Anthranilate 1,2-dioxygenase large subunit. | 0.833 |
| dmg_1 | gcvP | A3L23_02135 | A3L23_04177 | Dimethylglycine oxidase; Belongs to the GcvT family. | Putative glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.993 |
| dmg_1 | glyA1 | A3L23_02135 | A3L23_03011 | Dimethylglycine oxidase; Belongs to the GcvT family. | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.969 |
| dmg_1 | glyA2 | A3L23_02135 | A3L23_02144 | Dimethylglycine oxidase; Belongs to the GcvT family. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.969 |
| dmg_1 | soxA | A3L23_02135 | A3L23_02141 | Dimethylglycine oxidase; Belongs to the GcvT family. | Sarcosine oxidase subunit alpha. | 0.994 |
| dmg_1 | soxB | A3L23_02135 | A3L23_02143 | Dimethylglycine oxidase; Belongs to the GcvT family. | Sarcosine oxidase subunit beta. | 0.958 |
| dmg_1 | soxD | A3L23_02135 | A3L23_02142 | Dimethylglycine oxidase; Belongs to the GcvT family. | Sarcosine oxidase subunit delta. | 0.998 |
| dmg_1 | soxG | A3L23_02135 | A3L23_02140 | Dimethylglycine oxidase; Belongs to the GcvT family. | Sarcosine oxidase subunit gamma. | 0.998 |
| gcvP | dmg_1 | A3L23_04177 | A3L23_02135 | Putative glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Dimethylglycine oxidase; Belongs to the GcvT family. | 0.993 |
| gcvP | glyA1 | A3L23_04177 | A3L23_03011 | Putative glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.994 |
| gcvP | glyA2 | A3L23_04177 | A3L23_02144 | Putative glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.994 |
| gcvP | ltaE | A3L23_04177 | A3L23_00836 | Putative glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Low specificity L-threonine aldolase. | 0.972 |
| gcvP | soxA | A3L23_04177 | A3L23_02141 | Putative glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase subunit alpha. | 0.999 |
| gcvP | soxB | A3L23_04177 | A3L23_02143 | Putative glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase subunit beta. | 0.912 |
| gcvP | soxD | A3L23_04177 | A3L23_02142 | Putative glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase subunit delta. | 0.906 |