Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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leuA_32-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (603 aa)    
Predicted Functional Partners:
leuD
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 
 0.977
hacA
Homoaconitase large subunit.
 
 
 0.971
ilvE_2
Branched-chain-amino-acid aminotransferase.
  
 0.971
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.971
dmdB
2,3-dimethylmalate dehydratase small subunit.
  
 
 0.966
ilvE_1
Branched-chain-amino-acid aminotransferase.
  
 0.961
ilvH
Acetolactate synthase small subunit.
 
 
 0.951
ilvD_2
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.949
ilvB1
Acetolactate synthase large subunit IlvB1.
 
 
 0.948
AMY53492.1
Hypothetical protein.
 
 
 0.943
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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