| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| folB | folE | A3L23_02509 | A3L23_02507 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase 1. | 0.997 |
| folB | folK | A3L23_02509 | A3L23_02510 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.999 |
| folB | folP | A3L23_02509 | A3L23_02139 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.992 |
| folB | folP1 | A3L23_02509 | A3L23_02508 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase 1; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
| folB | ftsH_1 | A3L23_02509 | A3L23_02506 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.882 |
| folB | phoD_1 | A3L23_02509 | A3L23_02210 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Alkaline phosphatase D. | 0.905 |
| folB | phoD_2 | A3L23_02509 | A3L23_02940 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Alkaline phosphatase D. | 0.929 |
| folB | pld | A3L23_02509 | A3L23_03192 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Phospholipase D. | 0.929 |
| folB | ribBA | A3L23_02509 | A3L23_04358 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.709 |
| folE | folB | A3L23_02507 | A3L23_02509 | GTP cyclohydrolase 1. | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.997 |
| folE | folK | A3L23_02507 | A3L23_02510 | GTP cyclohydrolase 1. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.997 |
| folE | folP | A3L23_02507 | A3L23_02139 | GTP cyclohydrolase 1. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.944 |
| folE | folP1 | A3L23_02507 | A3L23_02508 | GTP cyclohydrolase 1. | Dihydropteroate synthase 1; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.993 |
| folE | ftsH_1 | A3L23_02507 | A3L23_02506 | GTP cyclohydrolase 1. | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.933 |
| folE | moaA2 | A3L23_02507 | A3L23_04790 | GTP cyclohydrolase 1. | Cyclic pyranopterin monophosphate synthase 2; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.917 |
| folE | phoD_1 | A3L23_02507 | A3L23_02210 | GTP cyclohydrolase 1. | Alkaline phosphatase D. | 0.909 |
| folE | phoD_2 | A3L23_02507 | A3L23_02940 | GTP cyclohydrolase 1. | Alkaline phosphatase D. | 0.932 |
| folE | pld | A3L23_02507 | A3L23_03192 | GTP cyclohydrolase 1. | Phospholipase D. | 0.932 |
| folE | ribBA | A3L23_02507 | A3L23_04358 | GTP cyclohydrolase 1. | Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.966 |
| folK | folB | A3L23_02510 | A3L23_02509 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |