Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
purRHTH-type transcriptional repressor PurR. (368 aa)    
Predicted Functional Partners:
ssaB
Manganese ABC transporter substrate-binding lipoprotein.
       0.760
gltB_1
Glutamate synthase [NADPH] large chain.
    
 
 0.736
gltB_2
Glutamate synthase [NADPH] large chain.
    
 
 0.736
pxpA
Hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
       0.552
kipI
Kinase A inhibitor.
       0.543
kipA_2
KipI antagonist.
       0.477
ptsH
Phosphocarrier protein HPr.
   
 
 0.471
znuC_1
Zinc import ATP-binding protein ZnuC.
       0.470
fruA
PTS system fructose-specific EIIABC component.
     
 0.466
znuB
High-affinity zinc uptake system membrane protein ZnuB.
       0.465
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
Server load: low (32%) [HD]