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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
menFPutative isochorismate synthase MenF. (357 aa)    
Predicted Functional Partners:
mbtB
Phenyloxazoline synthase MbtB.
  
  
 0.976
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
 0.976
dhbE
2,3-dihydroxybenzoate-AMP ligase.
 
  
 0.964
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.938
mbtI
Salicylate synthase.
  
  
0.935
phzD
Putative isochorismatase.
 
  
 0.926
tycC_3
Tyrocidine synthase 3.
 
  
 0.926
dhbF_1
Dimodular nonribosomal peptide synthase.
 
  
 0.925
tycC_1
Tyrocidine synthase 3.
 
  
 0.925
lgrD_4
Linear gramicidin synthase subunit D.
 
  
 0.925
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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