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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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clpC1_3ATP-dependent Clp protease ATP-binding subunit ClpC1. (167 aa)    
Predicted Functional Partners:
clpP2_3
ATP-dependent Clp protease proteolytic subunit 2; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
  
 
 0.895
AMY54188.1
Hypothetical protein.
     
 0.884
clpS
ATP-dependent Clp protease adapter protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
  
 
 0.819
htpG
Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.
  
 
 0.759
grpE
Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
 
 0.738
AMY52687.1
18 kDa heat shock protein; Belongs to the small heat shock protein (HSP20) family.
  
 
 0.725
AMY53254.1
18 kDa heat shock protein; Belongs to the small heat shock protein (HSP20) family.
  
 
 0.725
AMY54190.1
Hypothetical protein.
       0.716
lon_2
Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
  
 
 0.680
clpP2_1
ATP-dependent Clp protease proteolytic subunit 2; Belongs to the peptidase S14 family.
  
 
 0.652
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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