typA protein (Rhodococcus fascians D188) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

typA

GTP-binding protein TypA/BipA. (645 aa)

Predicted Functional Partners:

AMY54401.1

0.842

guaA_1

0.759

gltB_1

0.732

gltB_2

0.732

ychF

0.694

infC

0.636

rpmI

0.627

rhlE_3

0.627

rplA

0.616

rpsI

0.612

Your Current Organism:

Rhodococcus fascians D188

NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMY54401.1	typA	A3L23_03068	A3L23_03067	Putative monoacyl phosphatidylinositol tetramannoside-binding protein LpqW.	GTP-binding protein TypA/BipA.	0.842
gltB_1	gltB_2	A3L23_01850	A3L23_04027	Glutamate synthase [NADPH] large chain.	Glutamate synthase [NADPH] large chain.	0.999
gltB_1	guaA_1	A3L23_01850	A3L23_00183	Glutamate synthase [NADPH] large chain.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.849
gltB_1	typA	A3L23_01850	A3L23_03067	Glutamate synthase [NADPH] large chain.	GTP-binding protein TypA/BipA.	0.732
gltB_1	ychF	A3L23_01850	A3L23_03035	Glutamate synthase [NADPH] large chain.	Ribosome-binding ATPase YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	0.525
gltB_2	gltB_1	A3L23_04027	A3L23_01850	Glutamate synthase [NADPH] large chain.	Glutamate synthase [NADPH] large chain.	0.999
gltB_2	guaA_1	A3L23_04027	A3L23_00183	Glutamate synthase [NADPH] large chain.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.849
gltB_2	typA	A3L23_04027	A3L23_03067	Glutamate synthase [NADPH] large chain.	GTP-binding protein TypA/BipA.	0.732
gltB_2	ychF	A3L23_04027	A3L23_03035	Glutamate synthase [NADPH] large chain.	Ribosome-binding ATPase YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	0.525
guaA_1	gltB_1	A3L23_00183	A3L23_01850	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Glutamate synthase [NADPH] large chain.	0.849
guaA_1	gltB_2	A3L23_00183	A3L23_04027	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Glutamate synthase [NADPH] large chain.	0.849
guaA_1	infC	A3L23_00183	A3L23_04064	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	0.572
guaA_1	rplA	A3L23_00183	A3L23_02901	GMP synthase; Catalyzes the synthesis of GMP from XMP.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.949
guaA_1	rpmI	A3L23_00183	A3L23_04065	GMP synthase; Catalyzes the synthesis of GMP from XMP.	50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.	0.550
guaA_1	rpsI	A3L23_00183	A3L23_00208	GMP synthase; Catalyzes the synthesis of GMP from XMP.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.691
guaA_1	typA	A3L23_00183	A3L23_03067	GMP synthase; Catalyzes the synthesis of GMP from XMP.	GTP-binding protein TypA/BipA.	0.759
guaA_1	ychF	A3L23_00183	A3L23_03035	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Ribosome-binding ATPase YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	0.748
infC	guaA_1	A3L23_04064	A3L23_00183	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.572
infC	rplA	A3L23_04064	A3L23_02901	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.931
infC	rpmI	A3L23_04064	A3L23_04065	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.	0.986