Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ptsGPTS system glucose-specific EIICB component. (415 aa)    
Predicted Functional Partners:
crr
Glucose-specific phosphotransferase enzyme IIA component.
 0.999
nagA
N-acetylglucosamine-6-phosphate deacetylase.
 
  
 0.993
ptsH
Phosphocarrier protein HPr.
 
 
 0.978
nagB
Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
  
 0.950
glcB_1
PTS system glucoside-specific EIICBA component.
 
  
 0.924
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
  
 0.900
fruA
PTS system fructose-specific EIIABC component.
 
  
 0.868
nanK
N-acetylmannosamine kinase.
  
 
 0.859
glkA
Glucokinase.
  
 
 0.859
rbsK_1
Ribokinase.
  
  
 0.653
Your Current Organism:
Rhodococcus fascians D188
NCBI taxonomy Id: 1051973
Other names: R. fascians D188, Rhodococcus fascians str. D188, Rhodococcus fascians strain D188
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